Isosorbide nitrate tablets are medium-acting nitrate drugs, which have a longer duration of action than nitroglycerin, but a shorter duration of action than isosorbide mononitrate. Generally, it takes 15-20 minutes after taking the drug to take effect, and the duration of action can reach 4 hours. If patients take it sublingually during the onset of acute discomfort, the peak blood concentration can be reached in 6 minutes, and the duration of action is about 10-60 minutes. In clinical practice, it can be used to relieve painful symptoms caused by angina pectoris, coronary artery disease and myocardial infarction, and can be administered sublingually or orally, or by intravenous infusion, which is more potent than intravenous infusion. In addition, it can also be administered by spray or skin to relieve the patient’s discomfort.