There is a lifetime of liver cancer that does not recur, but the chances are relatively low. Liver cancer is divided into two categories: primary and secondary, both of which are relatively high recurrence rate tumors. For those who have timely surgical treatment at early stage and have good recovery after surgery, the recurrence rate is relatively lower, and there are also a few cases of lifelong non-recurrence. The prognosis of liver cancer is affected by many factors such as tumor stage, physical condition and treatment methods. The treatment should take into account the patient’s general condition and liver function, the size, location and number of tumors, and try to adopt individualized treatment plan, which may include ablation therapy, interventional therapy, or re-surgery. The prognosis of early-stage hepatocellular carcinoma undergoing radical surgery can be better, with the 5-year survival rate reaching 40%~70%, and the recurrence and metastasis rate of the tumor within 5 years after surgical resection is about 40%~70%. After surgery for liver cancer, it is necessary to have regular rechecks of alpha-fetoprotein, ultrasound, CT or MRI when necessary, so as to make a scientific assessment and strive for early detection and treatment of recurrence, and to seek medical treatment in time when uncomfortable symptoms appear.