The sore throat and inflammation after doing nucleic acid may be related to the inflammation of the pharynx itself, if it is triggered by viral infection, the main symptomatic treatment, such as avoiding tobacco and alcohol stimulation, drink more water, etc.; bacterial infection can be prescribed antibiotic treatment, such as cefixime, etc.; in addition, it may also be caused by local damage, generally can be relieved on their own. 1. Pharyngeal inflammation: If there is inflammation in the pharynx itself, it may cause local irritation during the pharyngeal secretion specimen collection process and aggravate the pain symptoms. Viral infections often need to take targeted treatment, drink more warm water, avoid smoking and drinking, do not eat spicy and irritating food; bacterial infections can follow the doctor’s advice to take cefixime, amoxicillin, roxithromycin and other sensitive antibiotics. 2. Local damage: If the mucous membrane of the pharynx is damaged due to improper operation, sore throat and inflammation can also occur, usually without special treatment, but should pay attention to reduce the use of the voice, avoid loud speech, drink warm water, wear a mask when going out and avoid eating stimulating food, the symptoms will gradually improve. If your throat is sore and inflamed after doing nucleic acid, and if your symptoms are not relieved, you should seek medical attention as soon as possible to find out the cause of the sore throat and take standardized treatment under the guidance of your physician to avoid delaying your condition.