The current use of PEEK materials has allowed for significant developments and advances in cranial repair surgery. With the large amount of titanium mesh material used in cranial repair surgery, more and more patients are experiencing problems with various diseases. In some cases, medical imaging examinations often appear shaded and inaccurate when patients are reviewed, making it difficult for physicians to determine the patient’s condition. Some patients experience adverse hot and cold reactions and suffer for long periods of time. The clinical application of PEEK materials is a good solution to these problems. Based on the biology of polymer materials, PEEK materials have good mechanical properties, easy plasticity, chemical stability and biocompatibility, can withstand high temperature steam and irradiation sterilization, and radioactive permeability and magnetic resonance scanning does not produce artifacts, less dense, lighter weight implants are more comfortable and do not conduct heat. The price for skull repair surgery is determined by the size of the defect, the size of the material, the cost of the examination, and other factors. Of course, patients with medical insurance can enjoy the reimbursement policy. Patients should choose a regular hospital for treatment to be assured of the regularity of the surgical material, and it is recommended that patients repair early and regain their health as soon as possible.