Treatment of pleural effusion depends on the cause. First, if it is caused by chest trauma, such as lung contusion, rib fracture, it is necessary to take strict bed rest, and the fracture broken end should be fixed, which can be fixed by rib fixation band or surgery. Second, if it is caused by lung inflammation and infection, it is necessary to apply antibiotics for anti-infection treatment, commonly used cephalosporins, penicillins, quinolones, macrolides and other drugs, which can achieve good anti-infection effect. Third, if it is caused by tumor, anti-tumor drug treatment should be carried out, such as radiotherapy and chemotherapy can effectively control the tumor foci. Fourth, if it is caused by tuberculosis, anti-tuberculosis treatment is needed, commonly used isoniazid, rifampicin, pyrazinamide, ethambutol and other drugs can also achieve good results. For patients with a relatively small amount of pleural effusion, it can be absorbed on its own. If the amount of effusion is relatively large and affects the function of the lungs, aspiration by empty needle puncture is needed to release the compression of the lungs and restore the normal function of the lungs.