Uncomfortable ankle suffocation can be caused by trauma, synovitis, and neoplastic lesions. 1. Trauma: If the ankle is severely impacted by external objects, it may lead to injury. After the injury, it is easy to cause ligament, tendon, synovial membrane, joint capsule and other tissues damage, causing local bleeding, forming hematoma, which causes ankle suffocation. 2. Synovitis: When synovitis occurs in the ankle, the synovitis tissue proliferates and becomes hypertrophied, and at the same time, a large amount of fluid leaks out and is confined in the ankle area, which causes the patient’s ankle to be distended and uncomfortable. 3. Tumor lesion: if there is tumor in ankle area, when the tumor proliferates and grows, it will erode and destroy the bone around the ankle, which will lead to fluid exudation and make the ankle suffocating. If the patient suffers from ankle swelling, it is suggested that the patient should go to the hospital in time to improve the examination of ankle area, X-ray, CT and other examinations, so as to clarify the cause of the disease, and follow the doctor’s instructions for treatment.