The treatment of elevated urea nitrogen needs to be combined with the specific disease. The most common one that can cause elevated urea nitrogen is chronic renal failure, which can be caused by a series of diseases such as chronic glomerulonephritis, diabetic nephropathy and hypertensive nephropathy. If before stage 4 of chronic renal failure, you can apply conservative treatment with drugs, such as UTI Qing granules and Haikun Renxi capsules. When chronic renal failure has entered the uremic phase, hemodialysis treatment needs to be given. In addition to these treatments, the underlying kidney disease, such as control of high blood pressure, blood sugar, etc., should be treated. Kidney transplantation can be performed if available, which is the best treatment for uremia. On the other hand, acute renal failure, in which acute tubular necrosis is the most common type, can cause urea elevation, for which nephrotoxic drugs, such as gentamicin and ibuprofen, should be avoided first, and short-term hemodialysis treatment can be given. In addition, the urine volume and renal function should be monitored dynamically, and adequate nutrition should be supplemented.