The lack of sexual pleasure may be caused by psychosomatic factors, painful intercourse, hypothyroidism, etc., and can be treated with general therapy, medication, and so on. 1. Psychological factors: may be due to excessive mental tension, stress or husband and wife relationship is not harmonious, can be improved by relaxing the state of mind, adjusting the relationship between husband and wife, and so on. 2. Painful sexual intercourse: it may be genital inflammation, resulting in pain during sex time will have no pleasure, the main anti-inflammatory treatment, such as bacterial infections caused by oral amoxicillin, cefadroxil, norfloxacin and other antibiotic drugs, and so on the inflammation under control and then sexual intercourse. 3. Hypothyroidism: often caused by a decrease in the synthesis and secretion of thyroid hormones, which can lead to a decrease in the excitability of the nervous system, so that sexual intercourse without pleasure, the need to actively replenish the thyroid hormones, most of them are taking levothyroxine sodium tablets for interventional therapy. There may be other reasons for the lack of sexual pleasure, it is recommended to actively seek medical advice, under the guidance of a professional physician for diagnosis and treatment. The above drugs need to be used under the guidance of a professional physician, to avoid blind use of drugs, so as not to aggravate the condition.