Itchy skin with red rash, may be related to contact dermatitis, eczema, hives and other diseases, in the treatment of the main target to give anti-inflammatory, anti-allergic drug treatment. 1. Contact dermatitis refers to the skin in contact with certain irritating objects, and produce a kind of perverse reaction, in the clinical most typical characteristics is the local skin rash accompanied by itching. In terms of treatment, the first thing to do is to remove the allergen, and then target some anti-allergy medication, such as topical dexamethasone cream, oral loratadine tablets and so on. 2. Eczema is a kind of inflammatory skin disease, in the acute exacerbation of the disease, the surface of the skin will appear with itching pimples, erythema, and even blisters, vesicles, etc., in the absence of obvious seepage, you can use topical glucocorticoid medication such as Dinocaprolactone cream. 3. Urticaria is an allergic disease that occurs in the subcutaneous blood vessels, and is mainly manifested in the clinic as itchy winds. The main treatment is to give anti-allergic drugs, such as oral levocetirizine capsules, chlorpheniramine maleate tablets and so on. For recurrent urticaria, allergen testing must be perfected as early as possible to clarify all allergens and avoid re-exposure. Itchy skin with red rashes may also be caused by other reasons, it is recommended to go to the dermatology department of the hospital in a timely manner, after clarifying the cause of the disease under the guidance of the doctor symptomatic treatment, do not self-medication.