Vitiligo can improve on its own in a few cases, and most of them need to rely on regular treatment to slow down the progress of the disease and control the condition. Vitiligo is a common acquired pigment loss skin and mucous membrane disease, can be induced by skin injury such as severe sunburn or cuts. Although some of the vitiligo has the possibility of self improvement, but the probability is low, it is recommended to follow the doctor’s instructions for regular treatment, so as to avoid the expansion of the area of the skin lesions and aggravation of the condition. The main treatments include topical glucocorticoid drugs, calcium-regulated phosphatase inhibitors, vitamin D3 derivatives, etc. If necessary, combined with physical therapy, such as 308nm excimer laser, narrow-spectrum ultraviolet treatment, stable vitiligo can be autologous epidermis or melanocyte transplantation treatment. The specific treatment effect varies from person to person, it is recommended to follow the doctor’s prescription medication after diagnosis.