If one side of the face is big and the other side is small because of chewing habits, heredity and other physiological factors, there is generally no need to correct. However, if it is caused by mumps, wisdom teeth pericoronitis and other diseases, it is necessary to take medication and surgical treatment for the cause of the disease. 1. Physiological factors: long-term use of one side of the chewing food, or heredity, may lead to one side of the face large and one side small. This kind of situation will not cause adverse effects on the body, and generally do not need to be corrected. Daily need to develop good eating habits, most can be relieved on their own. For people with cosmetic needs, Botox injections and face correction surgery are also available to improve the appearance of large and small faces. 2. Mumps: Mumps is also considered to be the cause of large and small faces. Patients can use antiviral drugs, such as ribavirin, under the guidance of doctors. Some patients can take physical cooling and oral antipyretic drugs, such as ibuprofen and acetaminophen, if they have high fever. After standardized treatment, facial asymmetry can be corrected. 3. Wisdom tooth pericoronitis: The face is big on one side and small on the other side, which may also be caused by wisdom tooth pericoronitis. Patients can follow the doctor’s instructions oral metronidazole, clindamycin and other antibiotics, or oral aspirin, ibuprofen and other pain medication. If necessary, incision and drainage, pericoronary gingival flap excision, wisdom tooth extraction, etc., can be taken to correct the symptoms of one side of the face is big and one side is small. There are many reasons for the face to be big on one side and small on the other side, and patients are advised to go to regular hospitals so as to find out the cause of the disease.