Wake up in the middle of the night and a variety of factors, such as physiological factors drink too much water leading to excessive urine production at night, the elderly sleep less, tension and stress, etc., pathological factors such as hyperthyroidism, etc., is not necessarily the body out of the problem. 1. Physiological factors: some physiological factors may lead to wake up at night, such as drinking too much water before going to bed, leading to excessive urine production at night, easy to wake up. The elderly due to sleep earlier, sleep time is also shorter, the middle of the night naturally easy to wake up the situation; daily life mental stress is too much long-term in a tense environment, which can easily lead to insomnia, sleep deprivation, waking up at night the situation. These are normal physiological phenomena, do not worry too much. 2. Pathological factors: certain pathological factors can also appear at night waking up, the symptoms of hyperthyroidism may also appear at night sleep deprivation, mental excitement, waking up at night. Other causes include heart failure, sleep apnea and hypoventilation syndrome. These are only some of the common causes. If you have severe sleep deprivation or are awake at night for a long period of time, it is recommended that you consult a doctor for a definitive diagnosis and standardized treatment as prescribed by the doctor.