The difference between Liu Wei Di Huang Wan and Wu Zi Yan Zong Wan is that one is for kidney yin deficiency and the other is for kidney yang deficiency. The efficacy of Liu Wei Di Huang Wan is mainly to nourish Yin, tonify blood, benefit essence and fill marrow. It is mainly used for kidney deficiency caused by overexertion, with common symptoms such as soreness and weakness of the waist and knees, heat in the hands and feet, hot flashes and night sweats, insomnia and dreaminess, etc. It is used for the treatment of back pain caused by excessive sexual activity and the adjunctive treatment of impotence and premature ejaculation in men and sexual frigidity in women. It is used to treat impotence, infertility, seminal emission, premature ejaculation, lumbago and post-urinary draining caused by kidney deficiency and essence deficiency.