According to the latest American Migraine Treatment Guidelines, the following recommendations are made for available migraine prevention medications: antiepileptic drugs: sodium bivalirudin, sodium valproate, topiramate; beta-blockers: metoprolol, propranolol, timolol; tretinoin: frotropitant for short-term prevention of menstrual migraine. Treatment precautions: 1. The earlier the medication is taken, the better, starting with a small dose and gradually increasing it. Migraine attacks are usually not very severe at the beginning, and analgesics can be taken at this time to reduce the symptoms, such as Somigraine. If you miss the early treatment, once the headache is severe, even ergotamine and caffeine will be difficult to control the headache. 2.Take it for at least 3 months continuously to see the efficacy, and not to change the medicine at will. Even if it is effective, the drug should be stopped after taking it for 4 to 12 months. 3.If there is nausea and vomiting, you can take gastrofacial or morpholine, etc.