Pathologic changes in atherosclerosis progress slowly but are usually irreversible and are most common after middle age. However, the progress of atherosclerosis can be slowed down through active control of risk factors, lifestyle intervention and drug treatment. 1. Active control of risk factors: including the treatment of hypertension, diabetes, dyslipidemia, obesity and other primary diseases. 2. Lifestyle intervention (1) Reasonable diet: control the total calorie intake per day, overweight or obese people should reduce the total calorie intake per day and reduce the intake of cholesterol. Patients with hypertension or heart failure should also limit salt intake. (2) Exercise therapy: Participating in appropriate amount of physical labor and sports activities is beneficial to the prevention of obesity, improvement of circulatory system function and adjustment of lipid metabolism, but the amount of physical activity should be based on their own physical condition and cardiac function, and gradual, not forced to do strenuous activities. (3) Reasonable arrangement of work and life: keep optimistic and happy mood, avoid excessive fatigue and emotional fluctuations. Ensure adequate sleep. (4) Quit smoking and limit alcohol: compared with non-smokers, the morbidity and mortality of smokers are 2-6 times higher, so it is recommended to quit smoking as early as possible to eliminate risk factors. 3. Drug therapy: patients with dyslipidemia should prefer statin lipid regulating drugs, such as atorvastatin, etc. Antiplatelet drugs such as aspirin and clopidogrel can also be used to prevent arterial thrombosis and embolism. The emergence of atherosclerosis, the need to actively seek medical advice, follow the doctor’s instructions for reasonable treatment, drugs need to be rationally applied under the guidance of a physician.