Symptoms and manifestations of adult pinworm disease are mainly perianal itching, gastrointestinal symptoms, mental symptoms and so on. 1. Perianal itching: pinworm disease is produced by pinworms produce toxic substances, toxins based perianal skin mucosa after itching, scratching caused by perianal skin shedding, congestion, rash, eczema, and even induced septic infection. 2. Digestive symptoms: pinworm toxin stimulation can cause loss of appetite, nausea, vomiting, abdominal pain, diarrhea and other symptoms. Pinworms can burrow into the intestinal mucosa, can also invade the appendix appendicitis, or even peritonitis. 3. Mental excitement: pinworm toxins will stimulate the human brain nerves, can appear insomnia and restlessness, irritability, etc., poor concentration. If the patient found pinworm disease, should be timely to the hospital for consultation, so that the condition is further controlled to prevent deterioration.