Whether chemotherapy is needed after surgery for liver cancer needs to be judged according to the specific situation of surgery and the specific pathological type of liver cancer of the patient, and cannot be generalized; if it cannot be cured after surgery, chemotherapy is needed. Liver cancer is a kind of malignant tumor, including primary liver cancer and metastatic liver cancer, which is usually treated with surgery as the main comprehensive treatment, and chemotherapy is usually used as an auxiliary treatment after surgery. For early stage liver cancer, no chemotherapy can be given after radical resection according to the situation. For larger tumors that cannot be completely resected by surgery or have positive margins, chemotherapy is often needed after surgery; if more tendency of intrahepatic metastasis is found during surgery, it is recommended to do transhepatic artery intrahepatic local embolization chemotherapy and so on. Therefore, whether chemotherapy is needed after liver cancer surgery should be decided according to the patient’s physical condition and doctor’s diagnosis, and should not be generalized.