Aging appearance is a symptom of progeria (Hutchinson-Gilford Syndrome), also known as progeria in children, which is a hereditary disease and was first reported by Hutchinson in 1886. In Hutchinson’s disease, the aging process of the body is 5 to 10 times faster than normal, and the patient looks like an old man. The organs of the patient also deteriorate quickly, resulting in a decline in physiological functions. Symptoms include thinness, hair loss and late teething. Children with this rare disease may look as if they are in their 60s or 70s, even though they are only 16 years old. Children with the disease usually live to be 7 to 20 years old, and most die of senile diseases such as cardiovascular disease, for which there is no effective treatment but only medication. Although the disease is a congenital disorder, it is uncertain whether it is autosomal recessive or dominant. The disease is a syndrome characterized by developmental delay and progressive age-related degenerative changes that occur by infancy. Diagnostic points of progeria-induced aging: The diagnosis of progeria-induced aging is based on the patient’s symptoms, and the patient’s appearance and growth record are quite important diagnostic bases. In addition to growth retardation, the most common signs in children with progeria are as follows: 1) typical bird-shaped head with baldness; 2) short stature and underweight; 3) thin limbs and joints that have become pronounced; 4) loss of subcutaneous fat; 5) a pear-shaped chest with a short clavicle; and 6) prominent veins.