For the treatment of liver nodules as described by the patient, the treatment varies depending on the benignity and malignancy of the liver nodules. Checking the upper abdominal ultrasound if it suggests nodular changes in the liver area, you need to determine what the nature of the nodule is. It depends on the presence of viral hepatitis. If there is no viral hepatitis and benign liver nodules appear, the patient is advised to observe further. If the nodules are small, it is recommended to continue to review the upper abdominal ultrasound or CT examination of the upper abdomen after 3 months, especially the enhanced CT has positive significance for the identification of the disease, for example, if the patient is a nodular hyperplasia in the liver area, no treatment is needed, only continued observation is required. If the blood test for methemoglobin indicates elevated methemoglobin, further enhanced CT or ultrasonography of the upper abdomen should be actively considered, and if necessary, ultrasound-guided puncture biopsy of the nodular area of the liver should be considered to determine whether further treatment is needed based on the biopsy results. If the biopsy result is a primary tumor of the liver, radiofrequency ablation should be actively considered for treatment. In addition, for some patients with combined viral hepatitis and elevated methemoglobin, dynamic observation is recommended, with a review of methemoglobin and enhanced CT of the upper abdomen every 3 months to determine the nature of the nodules in the liver. If it cannot be identified by imaging diagnosis, consider biopsy puncture or PET-CT under ultrasound guidance, and if it is malignant, surgical treatment should be considered as early as possible.