Alcohol should not be consumed when taking aspirin for the following reasons: First, both aspirin and alcohol can cause damage to the gastric mucosa, and the combination of the two will obviously aggravate gastric damage, sometimes even causing gastric ulcers and gastric bleeding. Second, both aspirin and alcohol can cause damage to the liver and kidneys, and this effect is significantly increased when the two are combined, which may lead to more serious liver and kidney function damage. Third, alcohol is metabolized into acetaldehyde in the body, which requires the enzyme acetaldehyde dehydrogenase to degrade alcohol into acetic acid, and aspirin has a significant inhibitory effect on this enzyme, which eventually leads to a significant increase in the concentration of alcohol, which cannot be easily metabolized, causing the accumulation of alcohol in the body and leading to alcoholism.
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