Eradication of type B acute lymphoblastic leukemia is relatively difficult, but some patients can achieve complete remission with aggressive treatment.
The prognosis of the disease is often related to age, white blood cell count at initial diagnosis, cellular and molecular genetics, and treatment sensitivity. Treatment modalities include supportive, chemotherapeutic, hematopoietic stem cell transplantation, and other treatments.
1.Clinical features: it often presents with anemia symptoms such as fatigue and lethargy, bleeding such as petechiae and ecchymosis, fever, and in young children, bone pain, lymph nodes and hepatosplenomegaly, etc. Children can be classified into low-risk, standard-risk, high-risk, and very high-risk groups, and adults have a relatively poor prognosis and tend to be in the standard-risk and high-risk groups.
2.Treatment
(1) Supportive treatment: blood transfusion, hemostasis, pain control and other symptomatic supportive treatment.
(2) Chemotherapy: based on Zoerythromycin and Mentholase regimen, as well as Vincristine, Prednisone, Methotrexate, Dexamethasone, etc. Complete remission can be achieved in some patients through chemotherapy, and adverse reactions such as infection, nausea, leukopenia, allergy, etc., are often seen.
(3) Hematopoietic stem cell transplantation: mainly applicable to patients with relapsed refractory, high-risk group, etc. Some patients can achieve complete remission through this treatment.
(4) Radiation therapy: mostly applicable to those with localized relapse.
Patients with B-lymphoblastic leukemia should receive standardized treatment and regular review in order to achieve the best therapeutic effect.