Intravertebral occupations are not necessarily tumors, but may be cysts, hemangiomas, or tuberculous lesions, and need to be analyzed and judged based on the specific problem. The presence of an intravertebral canal occupancy requires further clarification of its nature based on imaging evaluation, such as MRI, and localized lesions, requiring a high degree of vigilance for the possibility of malignant lesions. Lesions originating in the spinal canal are relatively rare, and it is generally more common for epithelial carcinoma or some sarcomas to metastasize locally through the hematologic system and form intravertebral lesions. Imaging helps to identify the nature of the corresponding disease, but the specific diagnosis needs to be based on the evidence obtained from pathological examination or whether the patient has a history of relevant malignancy, which may provide further corroboration for the diagnosis. Pain is the main manifestation of intravertebral occupations, and patients may seek medical attention for pain, which leads to the discovery of disease. Some lesions are found with localized nerve segmental lesions that cause motor or sensory abnormalities, and patients may present with urinary and defecation disorders. After a clear diagnosis is made, appropriate treatment needs to be given to improve the patient’s symptoms.