Sore throat during radiotherapy for laryngeal cancer patients can be relieved by medication as prescribed by doctor, and should also adjust the mentality and strengthen general life care. When laryngeal cancer patients have sore throat during radiotherapy, they can use pain relieving drugs such as ibuprofen and acetaminophen as prescribed by doctors. The pain is mainly related to the invasion of laryngeal tissues by cancer cells, which is easily accompanied by hoarseness, difficulty in swallowing and other symptoms. It is also considered to be related to radiation therapy damaging the normal tissues or cells of the body, which is easy to be accompanied by other conditions such as dry mouth, shedding of oral mucosa and laryngeal edema. In addition to the use of medication, some patients with pain in the throat and psychological overstress, anxiety has a certain relationship, so such patients need to adjust the state of mind, but also through listening to music and other ways to divert attention, which helps to improve the pain. In daily life, attention should be paid to strengthening oral care, avoiding intake of hard food, spicy and stimulating food, in order to reduce the stimulation and damage to local mucosa. It is suggested that people with sore throat after radiotherapy for laryngeal cancer should consult doctor for examination, and follow doctor’s instruction for treatment after clarifying the cause of pain, and should not use medicines or prescriptions indiscriminately on their own, so as not to cover up or aggravate the condition.