TORCH is an acronym for a group of pathogenic microorganisms, of which T (Toxoplasma) is Toxoplasma, R (Rubella.Virus) is Rubella virus, C (Cytomegalo.Virus) is Cytomegalovirus, and H (Herpes.Virus) is Herpes simplex type I/II. This group of microbial infections share common characteristics, namely, they can cause mother-infant infections. patients with TORCH syndrome cause miscarriages and stillbirths in pregnant women, and after birth, they have severe intellectual disabilities and cannot take care of themselves, causing great mental and economic burdens. About 26,000 children with TORCH are born each year in China, an average of 3 per hour, posing a great threat to eugenics and population quality. The virus can be transmitted through the placenta or birth canal to infect the fetus, especially in the first trimester when the embryo is in the organogenesis stage, when infection by the virus can destroy cells or inhibit cell division and proliferation. Infection with the virus after the organ-forming stage can destroy tissues and organ structures and can form a persistent infection that continues to detoxify after birth and can cause the corresponding pathology. At present, the most convenient and commonly used early screening method in China is to use ELISA enzyme immunoassay diagnostic technique. ELISA enzyme immunoassay test is to detect specific IgM and IgG antibodies in human serum, and we often regard IgG positivity as a previous infection, while IgM positivity is used as a diagnostic indicator of initial infection. Since IgM is an indicator of early infection and has a great impact on the fetus, the detection of IgM is of great concern. The detection of specific IgM in the placenta is a reliable basis for the diagnosis of intrauterine infection in the fetus.