Lowering creatinine can relieve the uncomfortable symptoms caused by renal insufficiency, such as reducing edema, relieving nausea, vomiting and stabilizing the internal environment. Generally speaking, the normal value of creatinine in adults is 53~106μmol/L for men and 44~97μmol/L for women, the reference range is different in different hospitals, please follow the standard of your local hospital. Elevated creatinine can be seen in acute and chronic renal failure, etc. Clinically, it can be manifested as nausea, vomiting, edema, dyspnea, hyperkalemia, hyperuricemia, anemia and so on. After lowering creatinine, renal function improves, edema can be reduced, improve cardiac function; relieve nausea, vomiting symptoms, improve ionic disorders, improve anemia, stabilize the body’s internal environment, etc., so as to significantly improve the quality of life. Clinical creatinine lowering mainly has drug treatment (such as urethane, renal failure), dialysis treatment (such as hemodialysis, peritoneal dialysis), surgical treatment (extracorporeal shockwave lithotripsy, renal transplantation) and so on. If you find elevated creatinine, it is recommended to go to regular hospitals in time to avoid delay in treatment.