It is best not to take Dazhongyin Pill and Zhi Bai Di Huang Wan together, as they are both yin tonics that nourish yin and reduce fire (nourish yin essence and lower fire), and taking them together may result in a superimposed effect and produce adverse reactions. Dazhongyin Pill is composed of ripened dihuang, tortoise board, cypress, and Zhimu, which has the function of nourishing yin and lowering fire, and is mainly used for treating the symptoms of yin deficiency and fire (deficiency of yin and essence in the body, with the appearance of hyperactive deficiency and fire). The main symptoms of this product are bone vapor and tidal fever (a burst of heat, feeling that the heat comes from the inside of the bone to the outside), night sweating (sweating abnormally after going to sleep, but the sweating stops after waking up), spermatorrhea, coughing and hematemesis, irritability, and pain and heat in the feet and knees. It is contraindicated in diabetes mellitus, people with cold and flu, and people with deficiency cold; it is also used with caution in pregnant women, patients with deficiency of qi and fever or actual fever, and people with weak spleen and stomach. Zhi Bai Di Huang Wan is composed of Zhi Mu, Huang Bai, Radix Rehmanniae Praeparata, Cornu Cervi Pantotrichum, Rhizoma Coptidis, Cornu Cervi Pantotrichum, Rhizoma Coptidis, Rhizoma Pinelliae, Poria. It nourishes the liver and kidney, nourishes yin and reduces fire, and treats bone vapor and tidal fever, spermatorrhea and night sweating caused by the evidence of yin deficiency and fire exuberance. Caution should be exercised in patients with actual fever, pregnant and lactating women, those with loose stools due to spleen deficiency, and patients with diabetes mellitus, hypertension, heart, liver, kidney and other chronic diseases should be advised by their doctors to use with caution. The best thing to do is not to take the two pills together, the two drugs belong to a class of efficacy and treatment, the composition of the same main drug, taken together may lead to superimposed effects. Yin deficiency and fire need to be under the guidance of a doctor to identify the severity of the choice to take one of the more reasonable, so as not to cause adverse effects.