Small blisters in the cracks of the hands are particularly itchy may be ringworm, eczema, contact dermatitis and other diseases resulting in symptoms. Patients should go to the hospital in time to find out the cause of the disease. 1. Ringworm: ringworm is due to dermatophyte infection of the skin of the hand caused by the disease, mainly involved in the thumb, palm and other parts. The patient will have the symptom of long blisters on the hands, and may also have the reaction of blister rupture, liquid exudation, itching and so on. 2. Eczema: Eczema is a chronic inflammatory itchy skin disease. Hand eczema patients will appear more obvious hand long blisters, itching and other symptoms, but also may appear skin erosion, plasma oozing. 3. Contact dermatitis: patients contact with allergens may lead to skin blisters symptoms, but also may appear skin redness, swelling, infection and other reactions. Patients with small blisters in the crevices of their hands that are particularly itchy should go to the hospital in a timely manner and under the guidance of the doctor for regular treatment.