As we all know, more than 90% of patients with chronic renal failure are accompanied by hypertension, how to choose and apply antihypertensive drugs for patients with chronic renal failure? It is better to start with a low dose and gradually increase the dose. What should I do if I miss an antihypertensive drug? Specific analysis of specific problems Long-acting antihypertensive drugs: generally do not need to take additional doses, the next time to take according to the time can be. Short-acting antihypertensive drugs: If the missed dose is longer than half of the interval between doses, the dose should be taken immediately and the next dose should be postponed appropriately. If you miss a dose at night, you do not have to take it unless there is a big fluctuation in blood pressure. When is the most appropriate time to take the medication? It is usually best to take it in the morning after waking up to control the blood pressure level throughout the 24 hours and during the day. Unless specifically ordered by your doctor, antihypertensive medications should not be taken at night. Can I break or chew my antihypertensive medication? If necessary, please read the instructions carefully.