Ovarian failure to ovulate may be due to lesions of the ovaries themselves, hormonal disorders, and systemic diseases that need to be treated according to the cause. 1. Ovarian lesions, such as polycystic ovary syndrome, premature ovarian failure, ovarian cancer and congenital underdevelopment, may occur ovarian failure to ovulate, these cases need to go to the hospital for treatment, such as according to the premature ovarian failure estrogen supplementation. 2. If the hypothalamus-pituitary-ovarian axis is dysfunctional, ovarian failure may occur, and clinical amenorrhea may even occur, so it is necessary to go to the hospital to inquire about the cause of this disorder before treatment. 3. Systemic diseases, such as very serious malnutrition, hyperthyroidism and other conditions will have a secondary effect on ovarian function, the emergence of non-ovulation, these still need to go to the disease for treatment, such as severe malnutrition for nutritional supplements, hyperthyroidism for surgery and other treatments. The causes of ovarian failure to ovulate are many and need to be treated symptomatically, and it is recommended that the patient actively follow up the treatment.