Radiofrequency ablation has applications in respiratory medicine. Radiofrequency ablation is a percutaneous puncture operation using ablation electrodes under ultrasound or CT guidance, or putting radiofrequency electrodes into solid tumor tissues in the process of surgery, killing tumor tissues directly through high temperature and letting the tumor tissues undergo coagulative necrosis, so as to achieve the purpose of local elimination of tumors. Radiofrequency ablation has more applications in respiratory department, which is suitable for patients with primary or metastatic lung cancer without surgical indication, patients with late-stage palliative treatment of lung cancer, patients with recurrence of lung cancer after surgery, remedial treatment of surgical exploration, and comprehensive treatment of tumor reduction. However, radiofrequency ablation is contraindicated in patients with coagulation disorders, heart or lung failure. The effect of radiofrequency ablation therapy is poorer and has certain risks in cases of vertebral metastasis, diffuse metastatic lesions in the lungs, severe emphysema, pulmonary fibrosis, severe pleural effusion, pulmonary hypertension, and tumor invasion of large blood vessels, etc. Radiofrequency ablation therapy is not recommended in such cases. Radiofrequency ablation treatment should be evaluated by doctors and operated by professionals.