White blood cells of 10,000 generally belong to the high situation, may be related to infection, rheumatic fever, tissue necrosis and other factors, as follows. 1. Infection: white blood cells are involved in the body’s defense function. When the body is infected, the granulocytes in the bone marrow will be released into the peripheral blood, resulting in an increase in the number of leukocytes in the peripheral blood, actively resisting infection. 2. Rheumatic fever: it is a disease closely related to streptococcal infection. If there is inflammation or infection in the body during an acute attack, there will be an increase in white blood cells. 3. Tissue necrosis: if there is tissue necrosis, local swelling, pain and other conditions, and may even be aseptic infection, which leads to leukocytosis. In short, if there is an abnormal increase in white blood cells, it is recommended to go to the hospital to find out the cause of the disease and take targeted symptomatic treatment to avoid delaying the condition.