Silymarin, or silymarin capsule, has no obvious harm to the kidneys, and is analyzed below in terms of pharmacological effects, metabolism and renal protection. 1. Pharmacological effects: Silymarin capsules have the effect of scavenging reactive oxygen species and peroxidized lipids, which can protect the cell membrane and promote the repair of damaged liver cells as well as promote the generation of new cells, and there is no damage to the kidneys themselves. 2. Metabolism: Silymarin capsules are insoluble in water, so after taking them, they are usually excreted through bile, and a very small part of them are excreted through urine, which has a relatively small effect on the kidneys. 3. Kidney protection: Silymarin capsules have antibacterial, anti-tumor and cardioprotective effects, for long-term use of anti-tumor and anti-immune drugs produced by renal toxicity has a protective effect. The common adverse reactions of Silymarin capsules include nausea, hiccups and chest tightness, etc. It is contraindicated during lactation and pregnancy. In addition, there are certain risks associated with the use of silymarin capsules and patients need to be supervised by a specialist.