If total bilirubin 27.2 μmol/L, direct bilirubin 8.4 μmol/L is caused by improper diet, it is not serious; if it is caused by hepatitis, cholelithiasis and other diseases, the condition is not serious in mild cases, but if it is not treated in time and the condition further develops, it is more serious. To determine whether total bilirubin 27.2 μmol/L and direct bilirubin 8.4 μmol/L are serious or not depends on the specific situation and cannot be generalized. Total bilirubin of 27.2μmol/L and direct bilirubin of 8.4μmol/L are above the normal range, but they are not serious if they are caused by alcohol abuse before the test, or eating too much oily, salty, or fatty food. If it is caused by hepatitis, cholelithiasis and other diseases, if the treatment is timely, the condition is mild and generally not serious; however, if the treatment is not timely, resulting in aggravation of the condition, it is more serious. In these cases, it is recommended to consult a doctor to find out the cause of the elevated bilirubin and to cooperate with the doctor for standardized treatment.