The situation of not being able to take vaccines should be judged according to the type of vaccine, and the common clinical vaccines include BCG vaccine, measles vaccine, hepatitis B vaccine, influenza vaccine, and new coronavirus vaccine. 1. BCG vaccine: If the patient has cardiovascular and cerebrovascular diseases, chronic kidney disease and other patients are prohibited. Those who are allergic to BCG vaccine should not be vaccinated. 2. Measles vaccine: pregnant women and patients with history of allergy to penicillin and egg should not be vaccinated. Meanwhile, patients with active tuberculosis, hematological diseases, malignant tumors, etc. are prohibited from vaccination. Meanwhile, patients with primary or secondary immunodeficiencies or those who have received immunosuppressive drugs are also prohibited from vaccination. Those who are allergic to any components of the vaccine should avoid vaccination. 3. Hepatitis B vaccine: If there is hepatitis, fever or acute or chronic serious diseases, it is not allowed to be vaccinated. For the early childhood there are neonatal asphyxia, jaundice, severe kidney malformation, premature birth weight less than 2.5kg, etc., also need to suspend vaccination, and have a history of allergy is prohibited. 4. Influenza vaccine: it is forbidden for patients with family or personal history of convulsions, and it is also forbidden for patients with chronic diseases, history of epilepsy, febrile illnesses, hyperthermia or acute infections. It is also prohibited for those who are allergic to any of the components of the vaccine. 5. New coronavirus vaccine: Vaccination is prohibited or postponed for those who are allergic to vaccine components, pregnant, in the process of developing a fever, suffering from an acute illness, with severe neurological disorders, or with uncontrolled severe chronic diseases. It is recommended to carefully understand the contraindications of the vaccine before vaccination and to administer the vaccine under the guidance of a doctor.