Sinusitis may cause a toothache. If a patient suffers from sinusitis and has a toothache at the same time, it is mainly considered to be caused by localized nasal lesions or gingival sinusitis. In addition, patients need to be alert to the possibility of dental disease. Sinusitis is an inflammatory disease of the sinuses. There are four pairs of sinuses in the body: maxillary sinus, septal sinus, frontal sinus, and pterygoid sinus. The maxillary sinus is the largest of the 4 pairs of sinuses, and the bottom wall is the alveolar bone. If the maxillary sinus becomes inflamed, the inflammatory reaction of the sinus cavity mucosa or the formation of pus may irritate and compress the dental nerve, which in turn may cause symptoms of tooth pain. If the patient is suffering from a gingival sinusitis, he or she may also experience toothache symptoms. Due to the root or periodontal infection, the mucosa of the ipsilateral maxillary sinus is involved, which in turn causes pain. In this case, the patient needs to wait for the inflammation to be controlled and then have the tooth removed to alleviate the discomfort. After the diagnosis of sinusitis, patients should choose suitable antibacterial drugs for treatment according to the pathogenic bacteria, commonly used are amoxicillin clavulanic acid potassium dispersible tablets and cefaclor capsules, etc. After sufficient treatment to control the inflammation, the pressure on the tooth root or alveolar nerve may be reduced and the pain will disappear. In addition, sinusitis toothache should be alerted to the presence of dental diseases such as dental caries, periapical periodontitis and periodontal abscess. If the patient happens to have dental disease at the same time as the sinusitis attack, the symptoms of sinusitis toothache may appear. At this time, patients should actively treat the original disease under the guidance of a professional doctor to avoid aggravation of the condition. Also pay attention not to eat cold, too acidic or too sweet food to avoid aggravating the toothache.