When most patients with diabetes mellitus develop diabetic nephropathy, they will have generalized edema, which may be related to the fact that diabetic nephropathy leaks a lot of protein resulting in hypoproteinemia. The treatment of diabetic generalized edema is as follows: 1, diet to control the intake of water, water, tea, soup, porridge, these try not to touch; 2, to the regular hospital after the doctor’s assessment, available some diuretic drugs to remove excess water in the body; 3, according to the patient’s protein, appropriate supplementation of high quality protein, serum albumin to the normal value of the range; 4, control the blood sugar to prevent Patients appear thirsty, resulting in drinking too much water, which in turn causes edema.