1.Signs and symptoms of optic nerve compression: As the tumor grows in the butterfly saddle, the upward development will compress the optic cross or optic nerve and cause the change of vision and visual field.
2, hypergonadotropic: prompting the target gland to secrete more sex hormones, men may initially have hyperactive sexual function, and then gradually decline. In women, they have less menstruation, amenorrhea, developed breasts, and lactation can be extended to several years after they stop breastfeeding.
3.Growth hormone hyperactivity: Eosinophilic pituitary adenoma occurs before epiphyseal closure (before adulthood) as gigantism, and after adulthood as acromegaly, and in between as mixed type.
4.Pituitary hyperfunction: Eosinophilic cells can produce growth hormone and oxytocin, while basophilic cells produce thyroid stimulating hormone, adrenal stimulating hormone and gonadotropin, etc.
5.Low pituitary function: The degree of low pituitary function is related to the degree of pressure on normal pituitary gland cells. As a result of hypopituitarism, the endocrine gland under its control atrophies and shows multiple dysfunctions.
6, endocrine and metabolic disorders symptoms and signs: pituitary gland endocrine function is very complex, mainly under the domination of the central nervous system, through the endocrine glands around the control of human growth, development, material metabolism and sex organs, sexual function and other physiological activities of regulation. The anterior pituitary gland is known to have six hormones, namely growth hormone, adrenocorticotropic hormone, prolactin, thyroid stimulating hormone and two gonadotropins. The posterior pituitary gland contains antidiuretic hormone and oxytocin, so posterior pituitary gland involvement can lead to uremia.
7, basophilic cell hyperfunction: thyrotropic, adrenal and gonadotropic hormones are affected, can produce Cushing’s syndrome, the patient manifested as centripetal obesity, to the face, neck and trunk more obvious, the limbs are relatively thin, face round like the full moon, red fat, often acne, upper back also has fat deposits, thin skin, with purple lines, marble-like.