Through the preliminary study, I believe that the beauty seekers already have a systematic and comprehensive understanding of hydrafacial injection. However, there are still some beauty seekers who have questions about the treatment principle of hydration injection. For example, why the hyaluronic acid in the hydrafacial injection can catch water, but the hyaluronic acid in the mask and cleanser can only be used as a wetting agent. Today we introduce the treatment principle of hydration injection based on this question. Skin hydration misconceptions Skin consists of epidermis, dermis and subcutaneous tissues, and contains accessory organs (hair, sweat glands, sebaceous glands, nails) as well as blood vessels, lymphatic vessels, nerves and muscles. The epidermis is located in the uppermost layer of the skin and is responsible for the protection of the skin and the metabolism of the cells. The dermis is located in the central layer of the skin and contains collagen, which makes the skin elastic and increases its flexibility and adaptability. The subcutaneous tissue consists of fat cells and loose connective tissue, which protects the cells of the upper layer and provides a cushioning effect to prevent external impacts. Topical hydration only provides moisture maintenance to the epidermis of the skin, while dietary intake is fluid water, which is difficult to be used by the skin, and these traditional hydration methods cannot fundamentally solve the problem of skin dehydration. Hyaluronic acid is one of the most important natural substances to maintain the health of the human body, from maintaining skin elasticity to lubricating joints, hyaluronic acid plays an important role, and at the same time can lock a large amount of water, forming an ultra-thin network of water molecules on the surface of the skin, strengthening the corneal layer hydration function, to achieve a strong water locking and moisturizing effect. Therefore, hydration is not just hydration, but targeted and precise replenishment of water locking substances, locking the water in the skin firmly. Mesotherapy The human primitive embryonic tissue is divided into ectoderm, mesoderm and endoderm. The ectoderm develops into skin (epidermis), brain, breast and sweat gland; the mesoderm develops into fibrous connective tissue (dermal subcutaneous tissue or called fascia), cartilage, bone, muscle and fat; the endoderm develops into digestive tract, liver, lung, pancreas, etc. “Mesotherapy”, also known as aesthetic therapy. It was introduced by Dr. Pistor in 1958. The prefix “meso-” was then used, leading to numerous mesotherapy series terms. Because he believed that the treatment was designed to work on the mesodermal tissue of the skin, hence the name “mesotherapy,” he said, “the treatment is centered around various treatments that work on the mesodermal tissue of the skin (vasculature, tendons, connective tissue, etc.). Because hyaluronic acid is most effective when injected into the dermal reticular layer, hydrafacial injections are small molecule non-cross-linked hyaluronic acid-based injections into the mesoderm for hydration purposes. Tip: Why does hyaluronic acid used in facial fillers last for about a year, but hyaluronic acid used in hydration injections only lasts for about a month? Although they are both hyaluronic acid, they cannot be mixed. The main difference between the two is the degree of cross-linking. The cross-linking agent (BDDE) can make hyaluronic acid form a net-like scaffold, and the higher the degree of cross-linking, the longer the maintenance time. The hyaluronic acid used in facial fillers has a high degree of cross-linking, so it lasts longer. It is injected deep into the dermis. It is usually like a pectin, thick enough to fill and shape. The hyaluronic acid used in hydration injection is small molecule non-cross-linked hyaluronic acid, which is thinner, just like water, and is injected at a very shallow level. If hyaluronic acid with a higher degree of cross-linking is used in the superficial layer of the skin, it will cause the skin to be hard and uneven.