Hepatitis B 145 positive means hepatitis B minor triplet. The severity of the disease in patients with minor third-positive hepatitis B is related to the degree of liver function damage and the absence of cirrhosis. If the patient’s liver function damage is relatively mild and there is no cirrhosis, the patient’s condition is not serious. If the patient’s liver function is severely impaired, bilirubin and transaminases are significantly elevated, and there are obvious gastrointestinal symptoms, yellow staining of the skin and sclera, darkening of the urine, and a significant decrease in prothrombin activity in laboratory tests, then the patient’s condition is more severe and requires timely treatment. If the patient has cirrhosis of the liver or with ascites and other manifestations, the condition is also more serious. For such patients, in addition to conventional liver protection, enzyme lowering, diuretic and other treatments, antiviral treatment is also required, and antiviral treatment requires long-term treatment, and some people need to take medication for life.