Creatinine 112μmol/L can’t determine how many stages of kidney disease a patient belongs to, chronic kidney disease staging should be judged according to glomerular filtration rate. The normal value of creatinine for adult men in China is 53-106μmol/L, and the normal value for women is 44-97μmol/L, and the reference range varies slightly from hospital to hospital. Creatinine 112μmol / L belongs to the high, divided into physiological factors and pathological causes. 1. Physiological factors such as high protein, eating a large amount of meat, strenuous exercise, etc. can cause a transient increase in creatinine, which can be restored to a healthy level after a vegetarian diet and rest. 2. Pathological elevation can be seen in acute and chronic renal failure, other secondary kidney diseases such as diabetic nephropathy, etc., which need to clarify the cause of the disease, and under the guidance of the doctor’s medication to slow down the progress of the disease. Chronic kidney disease is divided into 5 stages according to glomerular filtration rate, stage 1 GFR ≥90ml/min; stage 2 GFR 60-89ml/min-; stage 3a GFR 45-59ml/min-; stage 3b GFR 30-44ml/min-; stage 4 GFR 15-29ml/min; stage 5 GFR <15ml/min or dialysis. It is recommended to go to the hospital in time when the blood creatinine is found to be elevated, to clarify the cause of the disease, and to standardize the treatment under the doctor's guidance, so as to avoid delaying the condition.