Nasal congestion and sore throat should not use drugs indiscriminately, need to use drugs according to its cause, common diseases such as acute rhinitis, acute bronchitis, gastroesophageal reflux disease, etc., after a clear diagnosis, choose the anti-flu medicine, antibiotics, acid inhibitors and other medications. 1. Acute rhinitis: Acute rhinitis is caused by viral and bacterial infections, which can cause nasal congestion and sore throat. Treatment can follow the doctor’s instructions to use physiological sea saline for nasal rinsing, at the same time with cold medicine and antibiotic treatment, such as phenmetrazine tablets, ibuprofen tablets, Lianhua Qingdian capsule and amoxicillin and so on. 2. Acute bronchitis: acute bronchitis can also lead to nasal congestion and sore throat, should be to reduce talking, drink more water, ensure that the throat is moist. Treatment is based on antibiotics, sputum thinner, such as cefixime, cefdinir, bromhexine, ambroxol and so on. 3. Gastroesophageal reflux disease: This disease is caused by the reflux of gastric contents into the nasal cavity, nasopharynx and pharynx, commonly used proton pump inhibitors to inhibit acid therapy, such as omeprazole, pantoprazole. Nasal congestion and sore throat can not be used indiscriminately, it is recommended that patients go to the hospital in a timely manner, after a clear diagnosis of the use of medication as prescribed by the doctor, not to use drugs indiscriminately, so as not to lead to adverse consequences.