Whether calcification of the left lobe of the thyroid gland without nodules requires treatment should be decided on the basis of the specific condition under the guidance of a medical professional and should not be generalized. If calcification of the thyroid gland occurs along with abnormal thyroid function, treatment is usually required. If the thyroid gland becomes inflamed or necrotic, calcification may occur locally. If thyroid function is normal, treatment is usually not needed, and regular follow-up is recommended to monitor changes in thyroid calcification. Calcification of the left lobe of the thyroid gland without nodules, if the thyroid function is abnormal, including hyperthyroidism or hypothyroidism, this time need to be treated, if hyperthyroidism occurs, need to take oral propylmercaptoimidazole and other antithyroid drugs to treat, if hypothyroidism occurs, need to supplement the thyroid hormone. It is recommended to improve the thyroid function test, under the guidance of the doctor to decide whether the need for treatment.