Entecavir has the potential to rebound the virus if stopped for a month in between. Entecavir stopped for a month, this situation in the body of the number of viruses may be active again, once again the replication of the situation, at the same time there is a risk of inducing damage to liver function. So hepatitis B patients can not stop taking entecavir, if because of uncontrollable factors stopped for more than a month, it is recommended to resume drug treatment as soon as possible under the guidance of a doctor, do not casually stop using the drug in the future. Entecavir has been stopped for a month, it is recommended to go to the hospital to review the liver function, hepatitis B virus DNA quantification, liver ultrasound of the relevant indicators of a comprehensive assessment, under the guidance of the doctor, and then carry out the relevant treatment.