Constipation, anal itching, wiping the anus with fresh blood may be due to hemorrhoids, anal fissure, rectal prolapse and other causes. 1. Hemorrhoids: Hemorrhoids may be caused by poor dietary habits, ageing, poor defecation habits, long-term alcohol consumption, and a preference for spicy and irritating foods. Patients usually experience symptoms such as perianal prolapse, anal itching, blood in the stool, anal pain, etc. Symptoms may vary for different types of hemorrhoids. 2. Anal fissure: Anal fissure may be caused by long-term constipation, dry feces, trauma, excessive force during defecation, infection, narrowing of the anal canal and other reasons. Patients usually experience pain, constipation, bleeding and other symptoms. 3. Rectal prolapse: Rectal prolapse may be caused by malnutrition and increased abdominal pressure. Patients may experience constipation, diarrhea, enlarged prostate, chronic cough, rectal prolapse and other symptoms. To summarize, it is recommended that patients go to the hospital for a series of examinations in a timely manner to clarify the cause of the disease and give treatment as soon as possible to avoid delaying the condition.