If the alpha-fetoprotein exceeds the standard and reaches 700 after liver cancer surgery, this situation should be alert to the possibility of liver cancer recurrence after surgery. At present, there is no effective cure for liver cancer, and the risk of recurrence and metastasis after surgery is high, so most patients need to further cooperate with radiotherapy and chemotherapy treatment measures after surgery, so as to minimize the chance of recurrence of liver cancer after surgery, and help control the metastasis of cancer cells. Alpha-fetoprotein is a sensitive indicator to monitor the efficacy of liver cancer after surgery, and its normal value ranges from <25μg/L. If the alpha-fetoprotein is found to be obviously increased after surgery, first of all, we should be vigilant about the possibility of recurrence and metastasis of cancer cells, and we should further review the liver enhancement CT and PET-CT to help diagnose the disease. At the same time, patients need to keep a good mindset, consult doctors for review in a timely manner with the specific conditions of patients, and intervene as early as possible when problems are found, so as to maximally improve the quality of postoperative survival of patients with hepatocellular carcinoma.