Parkinson’s disease (PD), also known as tremor palsy, is a chronic disease of the central nervous system that affects the mobility of patients and occurs mostly in people older than middle age. It was developed by a British researcher named James Parkinson. Parkinson’s disease was first described by a British physician named James Parkinson in 1817, and later scholars used the name Parkinson’s disease as the basis for research. The early manifestations of the disease include resting tremor, muscle tonus, slow movement, difficulty starting movements, and abnormal posture. Other early symptoms include difficulty in starting activities, followed by frequent tremors in the arms and legs, and inability to perform fine movements in the upper extremities, resulting in difficulty in taking care of oneself in daily life, such as difficulty in dressing, taking off shoes, and washing. The main factors of disability are motor retardation, myotonia and postural disorders. Parkinson’s disease is often accompanied by depression, anxiety, limb pain and discomfort, constipation, excessive sweating, salivation, etc. This is how Li Liangxiu explained Parkinson’s disease to his kindergarten-aged daughter: “Parkinson’s disease is the disease that keeps you from moving.” Parkinson’s disease varies from person to person, with some people experiencing severe neurological damage and others doing a little better. People with the disease may start out with only one side of the body (the left or right side) affected, and soon after, symptoms may appear on both sides of the body. Generally, the condition changes over time, with different symptoms appearing at different times and becoming more severe. Usually, neither memory nor intelligence is affected in Parkinson’s disease. The most common symptoms are as follows: Tremors The most common symptom of Parkinson’s disease is involuntary shaking in one or both arms. In addition, there is shaking in the legs, feet or jaw. A slight movement of the part that is shaking will reduce the shaking, and the shaking usually does not occur during sleep. Stiff limbs or muscle contractures are caused by the brain’s message to relax not reaching the muscle tissue. Muscle stiffness can lead to muscle pain or inability to straighten the body. Another common symptom is bradykinesia, where normal movements such as getting in and out of bed, standing or sitting down require some effort to do. You may not be able to walk with a full stride, but instead walk in small steps. People with Parkinson’s disease sometimes experience “freezing”, a feeling of being unable to move on their own. Blinking, changes in facial expressions, swaying of the arms when walking, and other involuntary behaviors may be slower than normal. Lack of balance often causes the patient to fall. Other symptoms include abnormally slow and dull speech; shaking hands and smaller and smaller words when writing; and inability to swallow food. In addition, constipation is also one of the common symptoms of Parkinson’s disease The main treatment methods are as follows: Drugs 1, anticholinergics 2, antihistamines 3, levodopa-like drugs 4, dopamine agonists 5, monoamine oxidase B inhibitors 6, catecholamine oxygen site methyltransferase inhibitors Surgical treatment 1, pallidotomy that is destruction, the disadvantage of this surgery is the permanent destruction of the patient’s brain tissue, 2 DBS surgery is now a popular international treatment for Parkinson’s disease, the characteristics of this surgery are: expensive, bilateral, according to foreign reports there are patients using 8 years and very good results, it does not damage the brain, its treatment is reversible, also known as Parkinson’s disease “green treatment “When the power to the pacemaker is turned off, the symptoms of Parkinson’s disease will immediately appear. Hyperbaric oxygen Current clinical research shows that hyperbaric oxygen can play a considerable role in the treatment of Parkinson’s disease, and its efficacy is obvious if the treatment period is chosen properly. Hyperbaric oxygen treatment pressure 1.3 to 2.0 ATA, treatment time of 40-60min, general treatment for 8-12 courses. Hyperbaric oxygen therapy was applied simultaneously with the administration of drugs to improve intelligence and microcirculation, and the dosage and duration of drug therapy were the same as before hyperbaric oxygen therapy. After this treatment, all patients showed improvement in sensory and neurological conditions after 1 to 2 courses of hyperbaric oxygen therapy, such as improvement in mood, strengthening of thought processes and memory, facial expressions becoming active, increased mobility, improved gait, and disappearance of stereotyped monotonous symptoms. The pressure of hyperbaric oxygen therapy is generally 1.3 to 1.5 ATA, but when the clinical symptoms are mainly hyperkinetic tremor, the treatment pressure of 1.8 to 2.0 ATA is more effective. Hyperbaric oxygen is more effective than encephalitis in treating vascular Parkinson’s syndrome, and is most effective in vascular Parkinson’s syndrome under the age of 65 and within 1-5 years of disease duration, while it is relatively limited in treating limb tremor. Hyperbaric oxygen therapy should be continued for 6 months and then routinely repeated for 1 to 2 courses of treatment per year to stabilize the disease. The disease mostly affects middle-aged and elderly people, and there may be different degrees of age-related changes in cerebral arteries and central nervous system, which leads to relative hypoxia in brain tissue. Hyperbaric oxygen restores the function of degenerated nigrostriatal and nigrostriatal pathway nerve fibers by improving the hypoxic state, which leads to improved dopamine (DA) production and transport, and increased DA content. It has been suggested that one of the therapeutic mechanisms of hyperbaric oxygen for PD may be due to the scavenging of oxygen free radicals in PD patients by hyperbaric oxygen. It has been shown that hyperbaric oxygen enhances the efficacy of anti-PD drugs, allowing both compounds and monomeric forms of anti-PD drugs to be well utilized, thus enabling effective control of PD symptoms.