High glutamyl transferase and alkaline phosphatase should be treated differently according to different causes, which are mainly caused by alcoholic hepatitis, bile duct stones, hepatitis B and other diseases. 1. Alcoholic hepatitis: Alcoholic hepatitis is mostly caused by long-term alcohol consumption, and glutamyltransferase and alkaline phosphatase are indicators of liver function, so the indicators of alcoholic hepatitis will be elevated, and you can take silymarin and dicyclomine, and you should not consume alcohol in your normal life. 2. Biliary tract stones: diabetes, obesity, high cholesterol diet and genetic factors, environmental factors, etc. can induce biliary tract stones, biliary tract is located in the bile ducts in the liver, therefore, it will cause the elevation of glutamyltransferase and alkaline phosphatase, and it can be treated with laparoscopic cholecystectomy, open cholecystectomy, retrograde endoscopic cholangiopancreatography and stone removal. 3. Hepatitis B: Viral hepatitis is mainly caused by hepatitis B virus infection, mother-to-child transmission, blood or body fluids transmission may cause hepatitis B. Hepatitis B will cause damage to liver cells, which will lead to the elevation of glutamyl transferase and alkaline phosphatase, and it can be treated by the use of drugs such as entecavir tablets, tenofovir dipivoxil tablets and lamivudine tablets, etc. When the liver cells are damaged, it will cause the elevation of ght and alkaline phosphatase. When glutamyltransferase and alkaline phosphatase are high, it is recommended to go to the hospital for timely consultation, and the cause of the disease should be treated promptly.