Self-assessment of depression is not necessarily true. Self-assessment of depression is mainly based on the self-assessment scale of depression, which is subjective, that is, it is easily affected by situational factors, especially under the influence of negative emotions, and its self-assessment results tend to be heavy. Therefore, for the diagnosis of depression, clinically, it is mainly through the psychiatric specialty examination, the collection of psychiatric history, the measurement of the scale and the exclusion of related diseases, and the combination of the above information can be effectively determined, and finally arrive at the diagnosis of depression. Once the diagnosis of depression is made, systematic treatment is required in the clinic. Therefore, the diagnosis of depression requires the doctor’s comprehensive judgment, understanding, and ultimately effective treatment and diagnosis, which is very important in the clinic, and cannot be determined by the way of self-measurement scale to be sure that it belongs to depression.