There is no certain time when it is most appropriate to take antihypertensive drugs. The time to take antihypertensive drugs should be decided according to the different blood pressure fluctuation characteristics of each person. Taking antihypertensive drugs 2-3 hours before the peak of blood pressure can achieve a better effect of lowering blood pressure. Most people with hypertension have arytenoid hypertension, which is high blood pressure during the daytime. Most patients have two peaks of blood pressure during the day, one is about 2h after waking up in the morning, that is, about 8-10 o’clock in the morning, and the other peak is in the afternoon, about 16-18 o’clock. For these two peaks, patients are advised to choose before these two times when taking the medication. Patients take antihypertensive drugs every morning after waking up, when the antihypertensive drugs reach the best efficacy, basically when the patient’s first blood pressure peak is coming, can effectively control the blood pressure to within the normal range. At present, most of the commonly used antihypertensive drugs are long-acting drugs, so it is generally recommended that antihypertensive drugs be taken in the morning on an empty stomach, which can achieve a good effect of blood pressure control. Of course, there are also some patients with inverse arytenoid hypertension, that is, the blood pressure rises in the evening and lowers in the daytime. For such patients, it is recommended to choose to take antihypertensive drugs before bedtime. Of course, there are also a small number of patients who are prone to high blood pressure in the afternoon, you can take medication at noon under the guidance of a physician. In short, the time to take antihypertensive drugs should be based on the different blood pressure characteristics of each person to decide, in general, according to the arytenoid and anti arytenoid hypertension characteristics, often recommended to take in the morning on an empty stomach and before bedtime, the specifics of the regular hospital diagnosis and treatment of the doctor’s orders shall prevail.