After cirrhosis portal hypertension there will be opening of portal collateral circulation, the main collateral circulation can appear esophago-gastric fundus varices, abdominal wall varices, hemorrhoidal varices, and also splenomegaly. The spleen is enlarged due to prolonged bruising, and in severe cases, hypersplenism can occur, which is manifested by a decrease in peripheral blood leukocytes, erythrocytes, and platelets, and can even lead to bleeding, and ascites can also form. With further decompensation of liver function in portal hypertension, various complications of liver cirrhosis can occur, the more common one is the rupture and bleeding of esophageal – fundic varices, which is manifested as upper gastrointestinal bleeding. In addition, various infections can be secondary to spontaneous peritonitis, refractory ascites, hepatic encephalopathy, malignant transformation into hepatocellular carcinoma, hepatorenal syndrome, hepatopulmonary syndrome, portal vein thrombosis, and ionic disorders.